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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM67139
Substrate
n/a
Meas. Tech.
Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors
IC50
>55690±n/a nM
Citation
 PubChem, PC Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors PubChem Bioassay (2010)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM67139
Synonyms:
6,7-dimethoxy-2-(4-morpholinylmethylidene)-3-[(2-phenyl-4-oxazolyl)methyl]-1H-quinazolin-4-one | 6,7-dimethoxy-2-(morpholin-4-ylmethylidene)-3-[(2-phenyl-1,3-oxazol-4-yl)methyl]-1H-quinazolin-4-one | 6,7-dimethoxy-2-(morpholinomethylene)-3-[(2-phenyloxazol-4-yl)methyl]-1H-quinazolin-4-one | SR-03000001031-1 | cid_44202997
Type:
Small organic molecule
Emp. Form.:
C25H26N4O5
Mol. Mass.:
462.4977
SMILES:
COc1cc2nc(CN3CCOCC3)n(Cc3coc(n3)-c3ccccc3)c(=O)c2cc1OC
Structure:
Search PDB for entries with ligand similarity: