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Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM50757
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
6284±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM50757
Synonyms:
6-methoxy-2-(1-piperidinyl)-3-quinolinecarbonitrile | 6-methoxy-2-piperidin-1-yl-quinoline-3-carbonitrile | 6-methoxy-2-piperidin-1-ylquinoline-3-carbonitrile | 6-methoxy-2-piperidino-quinoline-3-carbonitrile | MLS000030943 | SMR000001678 | cid_649193
Type:
Small organic molecule
Emp. Form.:
C16H17N3O
Mol. Mass.:
267.3257
SMILES:
COc1ccc2nc(N3CCCCC3)c(cc2c1)C#N
Structure:
Search PDB for entries with ligand similarity: