Reaction Details Report a problem with these data
Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM67441
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
3962±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM67441
Synonyms:
4-(3-methyl-1-pyridin-1-iumyl)-5-[[(4-nitrophenyl)hydrazinylidene]methyl]-2-thiazololate | 4-(3-methylpyridin-1-ium-1-yl)-5-[[(4-nitrophenyl)hydrazinylidene]methyl]-1,3-thiazol-2-olate | 4-(3-methylpyridin-1-ium-1-yl)-5-[[(4-nitrophenyl)hydrazono]methyl]thiazol-2-olate | MLS001030197 | SMR000427297 | cid_3833004
Type:
Small organic molecule
Emp. Form.:
C16H13N5O3S
Mol. Mass.:
355.371
SMILES:
Cc1ccc[n+](c1)-c1[n-]c(=O)sc1CN=Nc1ccc(cc1)[N+]([O-])=O |w:15.17|
Structure:
Search PDB for entries with ligand similarity: