Reaction Details Report a problem with these data
Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM51301
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
4541±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM51301
Synonyms:
5-chloranyl-N-(6-methoxypyridin-3-yl)thiophene-2-sulfonamide | 5-chloro-N-(6-methoxy-3-pyridinyl)-2-thiophenesulfonamide | 5-chloro-N-(6-methoxy-3-pyridyl)thiophene-2-sulfonamide | 5-chloro-N-(6-methoxypyridin-3-yl)thiophene-2-sulfonamide | MLS000850485 | SMR000456503 | cid_2815587
Type:
Small organic molecule
Emp. Form.:
C10H9ClN2O3S2
Mol. Mass.:
304.773
SMILES:
COc1ccc(NS(=O)(=O)c2ccc(Cl)s2)cn1
Structure:
Search PDB for entries with ligand similarity: