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Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM34686
Substrate
n/a
Meas. Tech.
Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress
IC50
5410±n/a nM
Citation
 PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay (2010)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM34686
Synonyms:
3,5-dimethyl-4-{[(phenylsulfonyl)oxy]imino}-2,5-cyclohexadien-1-one | MLS000534017 | SMR000141453 | [(2,6-dimethyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate | [(2,6-dimethyl-4-oxocyclohexa-2,5-dien-1-ylidene)amino] benzenesulfonate | benzenesulfonic acid [(2,6-dimethyl-4-oxo-1-cyclohexa-2,5-dienylidene)amino] ester | benzenesulfonic acid [(4-keto-2,6-dimethyl-cyclohexa-2,5-dien-1-ylidene)amino] ester | cid_2221133
Type:
Small organic molecule
Emp. Form.:
C14H13NO4S
Mol. Mass.:
291.322
SMILES:
[#6]-[#6]1=[#6]-[#6](=O)-[#6]=[#6](-[#6])\[#6]-1=[#7]\[#8]S(=O)(=O)c1ccccc1 |t:1,5|
Structure:
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