Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM63203
Substrate
n/a
Meas. Tech.
Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress
IC50
>10000±n/a nM
Citation
 PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay (2010)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM63203
Synonyms:
2-[2-[(Z)-2-nitroethenyl]phenoxy]acetic acid ethyl ester | 2-[2-[(Z)-2-nitrovinyl]phenoxy]acetic acid ethyl ester | MLS000586023 | SMR000204386 | cid_5286552 | ethyl 2-[2-[(Z)-2-nitroethenyl]phenoxy]acetate | ethyl 2-[2-[(Z)-2-nitroethenyl]phenoxy]ethanoate | ethyl {2-[(Z)-2-nitrovinyl]phenoxy}acetate
Type:
Small organic molecule
Emp. Form.:
C12H13NO5
Mol. Mass.:
251.2353
SMILES:
CCOC(=O)COc1ccccc1\C=C/[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: