Reaction Details Report a problem with these data
Target
UDP-galactopyranose mutase
Ligand
BDBM68225
Substrate
n/a
Meas. Tech.
High-throughput FP Assay
IC50
4.1e+4±n/a nM
Kd
4.9e+3± 2e+2 nM
Citation
 Carlson, EE; May, JF; Kiessling, LL Chemical probes of UDP-galactopyranose mutase. Chem Biol 13:825-37 (2006) [PubMed]  Article 
Target
Name:
UDP-galactopyranose mutase
Synonyms:
GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf
Type:
Protein
Mol. Mass.:
45807.82
Organism:
Mycobacterium tuberculosis H37Rv
Description:
P9WIQ1
Residue:
399
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
  
Inhibitor
Name:
BDBM68225
Synonyms:
Thiazolidinone core, 9
Type:
Small organic molecule
Emp. Form.:
C16H8Cl3N3O4
Mol. Mass.:
412.611
SMILES:
Clc1ccc(cc1Cl)N1NC(=O)C(=Cc2ccc(Cl)c(c2)N(=O)=O)C1=O |w:13.14|
Structure:
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