Reaction Details Report a problem with these data
Target
UDP-galactopyranose mutase
Ligand
BDBM68226
Substrate
n/a
Meas. Tech.
High-throughput FP Assay
IC50
28±n/a nM
Kd
5.3e+3± 5e+2 nM
Citation
 Carlson, EE; May, JF; Kiessling, LL Chemical probes of UDP-galactopyranose mutase. Chem Biol 13:825-37 (2006) [PubMed]  Article 
Target
Name:
UDP-galactopyranose mutase
Synonyms:
GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf
Type:
Protein
Mol. Mass.:
45807.82
Organism:
Mycobacterium tuberculosis H37Rv
Description:
P9WIQ1
Residue:
399
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
  
Inhibitor
Name:
BDBM68226
Synonyms:
Thiazolidinone core, 10
Type:
Small organic molecule
Emp. Form.:
C16H8ClN3O4S
Mol. Mass.:
373.77
SMILES:
Oc1cc(Cl)c(\C=c2/sc3nc4ccccc4n3c2=O)cc1N(=O)=O
Structure:
Search PDB for entries with ligand similarity: