Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM68315
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM68315
Synonyms:
MLS-0435541.0001 | N-(5-morpholin-4-ylsulfonyl-2-pyrrolidin-1-yl-phenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | N-(5-morpholin-4-ylsulfonyl-2-pyrrolidin-1-ylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | N-(5-morpholinosulfonyl-2-pyrrolidino-phenyl)-4,5,6,7-tetrahydrobenzothiophene-2-carboxamide | N-[5-(4-morpholinylsulfonyl)-2-(1-pyrrolidinyl)phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | cid_17460708
Type:
Small organic molecule
Emp. Form.:
C23H29N3O4S2
Mol. Mass.:
475.624
SMILES:
O=C(Nc1cc(ccc1N1CCCC1)S(=O)(=O)N1CCOCC1)c1cc2CCCCc2s1
Structure:
Search PDB for entries with ligand similarity: