Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM68303
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM68303
Synonyms:
3-methoxy-N-(2-methoxy-5-morpholin-4-ylsulfonyl-phenyl)-4-(2-methylpropoxy)benzamide | 3-methoxy-N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)-4-(2-methylpropoxy)benzamide | 3-methoxy-N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]-4-(2-methylpropoxy)benzamide | 4-isobutoxy-3-methoxy-N-(2-methoxy-5-morpholinosulfonyl-phenyl)benzamide | MLS-0413763.0001 | cid_16250706
Type:
Small organic molecule
Emp. Form.:
C23H30N2O7S
Mol. Mass.:
478.559
SMILES:
COc1ccc(cc1NC(=O)c1ccc(OCC(C)C)c(OC)c1)S(=O)(=O)N1CCOCC1
Structure:
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