Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM68310
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM68310
Synonyms:
MLS-0435536.0001 | N-(2-isopropoxy-5-morpholinosulfonyl-phenyl)benzothiophene-2-carboxamide | N-(5-morpholin-4-ylsulfonyl-2-propan-2-yloxy-phenyl)-1-benzothiophene-2-carboxamide | N-(5-morpholin-4-ylsulfonyl-2-propan-2-yloxyphenyl)-1-benzothiophene-2-carboxamide | N-[5-(4-morpholinylsulfonyl)-2-propan-2-yloxyphenyl]-1-benzothiophene-2-carboxamide | cid_16282645
Type:
Small organic molecule
Emp. Form.:
C22H24N2O5S2
Mol. Mass.:
460.566
SMILES:
CC(C)Oc1ccc(cc1NC(=O)c1cc2ccccc2s1)S(=O)(=O)N1CCOCC1
Structure:
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