Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM68316
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM68316
Synonyms:
5-ethyl-N-(2-methoxy-5-morpholin-4-ylsulfonyl-phenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | 5-ethyl-N-(2-methoxy-5-morpholin-4-ylsulfonylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | 5-ethyl-N-(2-methoxy-5-morpholinosulfonyl-phenyl)-4,5,6,7-tetrahydrobenzothiophene-2-carboxamide | 5-ethyl-N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide | MLS-0435542.0001 | cid_24242928
Type:
Small organic molecule
Emp. Form.:
C22H28N2O5S2
Mol. Mass.:
464.598
SMILES:
CCC1CCc2sc(cc2C1)C(=O)Nc1cc(ccc1OC)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: