Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM68320
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM68320
Synonyms:
3-[4-(2-ethoxyphenyl)piperazin-1-yl]carbonyl-N,N-dimethyl-4-pyrrolidin-1-yl-benzenesulfonamide | 3-[4-(2-ethoxyphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylbenzenesulfonamide | 3-[[4-(2-ethoxyphenyl)-1-piperazinyl]-oxomethyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide | MLS-0421957.0001 | N,N-dimethyl-3-(4-o-phenetylpiperazine-1-carbonyl)-4-pyrrolidino-benzenesulfonamide | cid_25161603
Type:
Small organic molecule
Emp. Form.:
C25H34N4O4S
Mol. Mass.:
486.627
SMILES:
CCOc1ccccc1N1CCN(CC1)C(=O)c1cc(ccc1N1CCCC1)S(=O)(=O)N(C)C
Structure:
Search PDB for entries with ligand similarity: