Reaction Details Report a problem with these data
Target
Krueppel-like factor 5
Ligand
BDBM70199
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)
IC50
>39841±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay (2010)[AID] 
Target
Name:
Krueppel-like factor 5
Synonyms:
BTEB2 | CKLF | IKLF | KLF5 | KLF5_HUMAN | Kruppel-like factor 5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50808.71
Organism:
Homo sapiens (Human)
Description:
Q13887
Residue:
457
Sequence:
MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN
  
Inhibitor
Name:
BDBM70199
Synonyms:
2-(3,4-dimethylphenoxy)-N-[2-[3-(trifluoromethyl)phenyl]-5-benzotriazolyl]acetamide | 2-(3,4-dimethylphenoxy)-N-[2-[3-(trifluoromethyl)phenyl]benzotriazol-5-yl]acetamide | 2-(3,4-dimethylphenoxy)-N-[2-[3-(trifluoromethyl)phenyl]benzotriazol-5-yl]ethanamide | SR-01000528153 | SR-01000528153-2 | cid_1114257
Type:
Small organic molecule
Emp. Form.:
C23H19F3N4O2
Mol. Mass.:
440.4178
SMILES:
Cc1ccc(OCC(=O)Nc2ccc3nn(nc3c2)-c2cccc(c2)C(F)(F)F)cc1C
Structure:
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