Reaction Details Report a problem with these data
Target
Krueppel-like factor 5
Ligand
BDBM70206
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)
IC50
>39841±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay (2010)[AID] 
Target
Name:
Krueppel-like factor 5
Synonyms:
BTEB2 | CKLF | IKLF | KLF5 | KLF5_HUMAN | Kruppel-like factor 5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50808.71
Organism:
Homo sapiens (Human)
Description:
Q13887
Residue:
457
Sequence:
MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN
  
Inhibitor
Name:
BDBM70206
Synonyms:
(6-fluoro-1,3-benzothiazol-2-yl)-(6-isopropyl-1,3-benzothiazol-2-yl)amine | N-(6-fluoranyl-1,3-benzothiazol-2-yl)-6-propan-2-yl-1,3-benzothiazol-2-amine | N-(6-fluoro-1,3-benzothiazol-2-yl)-6-propan-2-yl-1,3-benzothiazol-2-amine | SR-03000001323 | SR-03000001323-1 | cid_7109986
Type:
Small organic molecule
Emp. Form.:
C17H14FN3S2
Mol. Mass.:
343.442
SMILES:
CC(C)c1ccc2nc(Nc3nc4ccc(F)cc4s3)sc2c1
Structure:
Search PDB for entries with ligand similarity: