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Target
Krueppel-like factor 5
Ligand
BDBM70212
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1)
IC50
285.43±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify inhibitors of kruppel-like factor 5 (KLF5): luminescence-based cell-based dose response assay for inhibitors of KLF5 (Round 1) PubChem Bioassay (2010)[AID] 
Target
Name:
Krueppel-like factor 5
Synonyms:
BTEB2 | CKLF | IKLF | KLF5 | KLF5_HUMAN | Kruppel-like factor 5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50808.71
Organism:
Homo sapiens (Human)
Description:
Q13887
Residue:
457
Sequence:
MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN
  
Inhibitor
Name:
BDBM70212
Synonyms:
3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-(4-ethoxyphenyl)propanamide | 3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-p-phenetyl-propionamide | SR-03000001329 | SR-03000001329-1 | cid_1249379
Type:
Small organic molecule
Emp. Form.:
C23H27N3O3
Mol. Mass.:
393.4788
SMILES:
CCOc1ccc(NC(=O)CCc2nc(no2)-c2ccc(cc2)C(C)(C)C)cc1
Structure:
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