Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67424
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
>8387±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67424
Synonyms:
(6E)-2-allyl-6-[[(3,5-dimethyl-1,2,4-triazol-4-yl)amino]methylene]cyclohexa-2,4-dien-1-one | (6E)-6-[[(3,5-dimethyl-1,2,4-triazol-4-yl)amino]methylidene]-2-prop-2-enyl-1-cyclohexa-2,4-dienone | (6E)-6-[[(3,5-dimethyl-1,2,4-triazol-4-yl)amino]methylidene]-2-prop-2-enyl-cyclohexa-2,4-dien-1-one | (6E)-6-[[(3,5-dimethyl-1,2,4-triazol-4-yl)amino]methylidene]-2-prop-2-enylcyclohexa-2,4-dien-1-one | 2-Allyl-6-{[(E)-3,5-dimethyl-[1,2,4]triazol-4-ylimino]-methyl}-phenol | MLS000551401 | SMR000145326 | cid_5342927
Type:
Small organic molecule
Emp. Form.:
C14H16N4O
Mol. Mass.:
256.303
SMILES:
Cc1nnc(C)n1N=Cc1cccc(CC=C)c1O |w:7.7|
Structure:
Search PDB for entries with ligand similarity: