Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM51067
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
5219±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM51067
Synonyms:
3-aminobenzoic acid [2-[(9,10-diketo-1-anthryl)amino]-2-keto-ethyl] ester | 3-aminobenzoic acid [2-[(9,10-dioxo-1-anthracenyl)amino]-2-oxoethyl] ester | MLS000334016 | SMR000248774 | [2-[(9,10-dioxoanthracen-1-yl)amino]-2-oxoethyl] 3-aminobenzoate | [2-[[9,10-bis(oxidanylidene)anthracen-1-yl]amino]-2-oxidanylidene-ethyl] 3-azanylbenzoate | cid_4009020
Type:
Small organic molecule
Emp. Form.:
C23H16N2O5
Mol. Mass.:
400.3835
SMILES:
Nc1cccc(c1)C(=O)OCC(=O)Nc1cccc2C(=O)c3ccccc3C(=O)c12
Structure:
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