Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67428
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
10447±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67428
Synonyms:
(E)-2-cyano-3-(2-nitrophenyl)-N-prop-2-enyl-2-propenamide | (E)-2-cyano-3-(2-nitrophenyl)-N-prop-2-enyl-prop-2-enamide | (E)-2-cyano-3-(2-nitrophenyl)-N-prop-2-enylprop-2-enamide | (E)-N-allyl-2-cyano-3-(2-nitrophenyl)acrylamide | MLS000391528 | SMR000260563 | cid_2378168
Type:
Small organic molecule
Emp. Form.:
C13H11N3O3
Mol. Mass.:
257.2447
SMILES:
[O-][N+](=O)c1ccccc1\C=C(/C#N)C(=O)NCC=C
Structure:
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