Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM51118
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
4534±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM51118
Synonyms:
2-[3-(2-amino-5-bromo-phenyl)-2-keto-quinoxalin-1-yl]acetic acid ethyl ester | 2-[3-(2-amino-5-bromophenyl)-2-oxo-1-quinoxalinyl]acetic acid ethyl ester | MLS000121244 | SMR000118648 | [3-(2-Amino-5-bromo-phenyl)-2-oxo-2H-quinoxalin-1-yl]-acetic acid ethyl ester | cid_1548304 | ethyl 2-[3-(2-amino-5-bromophenyl)-2-oxoquinoxalin-1-yl]acetate | ethyl 2-[3-(2-azanyl-5-bromanyl-phenyl)-2-oxidanylidene-quinoxalin-1-yl]ethanoate
Type:
Small organic molecule
Emp. Form.:
C18H16BrN3O3
Mol. Mass.:
402.242
SMILES:
CCOC(=O)Cn1c2ccccc2nc(-c2cc(Br)ccc2N)c1=O
Structure:
Search PDB for entries with ligand similarity: