Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM51301
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
6301±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM51301
Synonyms:
5-chloranyl-N-(6-methoxypyridin-3-yl)thiophene-2-sulfonamide | 5-chloro-N-(6-methoxy-3-pyridinyl)-2-thiophenesulfonamide | 5-chloro-N-(6-methoxy-3-pyridyl)thiophene-2-sulfonamide | 5-chloro-N-(6-methoxypyridin-3-yl)thiophene-2-sulfonamide | MLS000850485 | SMR000456503 | cid_2815587
Type:
Small organic molecule
Emp. Form.:
C10H9ClN2O3S2
Mol. Mass.:
304.773
SMILES:
COc1ccc(NS(=O)(=O)c2ccc(Cl)s2)cn1
Structure:
Search PDB for entries with ligand similarity: