Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67447
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
>25109±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67447
Synonyms:
MLS001125706 | N-[[5-(4-bromanyl-2-nitro-phenyl)furan-2-yl]methylideneamino]-5-methyl-furan-2-carboxamide | N-[[5-(4-bromo-2-nitro-phenyl)-2-furyl]methyleneamino]-5-methyl-2-furamide | N-[[5-(4-bromo-2-nitrophenyl)-2-furanyl]methylideneamino]-5-methyl-2-furancarboxamide | N-[[5-(4-bromo-2-nitrophenyl)furan-2-yl]methylideneamino]-5-methylfuran-2-carboxamide | SMR000659155 | cid_1362960
Type:
Small organic molecule
Emp. Form.:
C17H12BrN3O5
Mol. Mass.:
418.198
SMILES:
Cc1ccc(o1)C(=O)N\N=C\c1ccc(o1)-c1ccc(Br)cc1[N+]([O-])=O
Structure:
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