Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM53372
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
39575±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM53372
Synonyms:
MLS001099293 | N-(6-amino-2,4-diketo-1-propyl-pyrimidin-5-yl)-N-(2-methoxyethyl)-2-(5-morpholinosulfonyl-2-thienyl)acetamide | N-(6-amino-2,4-dioxo-1-propyl-5-pyrimidinyl)-N-(2-methoxyethyl)-2-[5-(4-morpholinylsulfonyl)-2-thiophenyl]acetamide | N-(6-amino-2,4-dioxo-1-propylpyrimidin-5-yl)-N-(2-methoxyethyl)-2-(5-morpholin-4-ylsulfonylthiophen-2-yl)acetamide | N-[6-azanyl-2,4-bis(oxidanylidene)-1-propyl-pyrimidin-5-yl]-N-(2-methoxyethyl)-2-(5-morpholin-4-ylsulfonylthiophen-2-yl)ethanamide | SMR000713735 | cid_24687447
Type:
Small organic molecule
Emp. Form.:
C20H29N5O7S2
Mol. Mass.:
515.604
SMILES:
CCCn1c(N)c(N(CCOC)C(=O)Cc2ccc(s2)S(=O)(=O)N2CCOCC2)c(=O)[nH]c1=O
Structure:
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