Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67453
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
8337±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67453
Synonyms:
MLS002276353 | SMR001317988 | cid_44202984
Type:
Small organic molecule
Emp. Form.:
C32H57N3O6S9
Mol. Mass.:
868.396
SMILES:
Nc1ncc[nH]1.[H][C@@]12CC[C@@H](C(C)CCC(C)C(C)(C)C)[C@@]1(C)CC[C@@]1([H])C2C[C@H](OS(O)(=S)=S)[C@@]2([H])C[C@H](OS(O)(=S)=S)[C@H](C[C@]12C)OS(O)(=S)=S
Structure:
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