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Target
Heat shock factor protein 1
Ligand
BDBM72395
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)
EC50
>260000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM72395
Synonyms:
1-ethyl-4-[(methyl{[3-(phenoxymethyl)-1,2,4-oxadiazol-5-yl]methyl}amino)methyl]pyrrolidin-2-one | 1-ethyl-4-[[methyl-[[3-(phenoxymethyl)-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]-2-pyrrolidinone | 1-ethyl-4-[[methyl-[[3-(phenoxymethyl)-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]-2-pyrrolidone | 1-ethyl-4-[[methyl-[[3-(phenoxymethyl)-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]pyrrolidin-2-one | MLS000734696 | SMR000317967 | cid_16187726
Type:
Small organic molecule
Emp. Form.:
C18H24N4O3
Mol. Mass.:
344.4082
SMILES:
CCN1CC(CN(C)Cc2nc(COc3ccccc3)no2)CC1=O
Structure:
Search PDB for entries with ligand similarity: