Reaction Details Report a problem with these data
Target
Protein LANA1
Ligand
BDBM74308
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction
EC50
>75000±n/a nM
Citation
 PubChem, PC Fluorescence Polarization Cell-Free Homogeneous Dose Retest to Confirm Inhibitors of the LANA Histone H2A/H2B Interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein LANA1
Synonyms:
LANA | LANA1 | LANA1_HHV8P
Type:
Enzyme Catalytic Domain
Mol. Mass.:
131093.36
Organism:
Human herpesvirus 8
Description:
Q9QR71
Residue:
1129
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
  
Inhibitor
Name:
BDBM74308
Synonyms:
4-[(3-nitrophenyl)sulfonylamino]-N-(4-oxidanylcyclohexyl)benzamide | MLS002180713 | N-(4-hydroxycyclohexyl)-4-[(3-nitrophenyl)sulfonylamino]benzamide | SMR001269743 | cid_25162777
Type:
Small organic molecule
Emp. Form.:
C19H21N3O6S
Mol. Mass.:
419.452
SMILES:
OC1CCC(CC1)NC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)[N+]([O-])=O)cc1 |(4.41,-8.23,;4.41,-6.69,;5.75,-5.92,;5.75,-4.38,;4.41,-3.61,;3.08,-4.38,;3.08,-5.92,;4.41,-2.07,;5.75,-1.3,;7.08,-2.07,;5.75,.24,;4.41,1.01,;4.41,2.55,;5.75,3.32,;5.75,4.86,;7.08,5.63,;6.31,6.96,;7.85,4.3,;8.41,6.4,;8.41,7.94,;9.75,8.71,;11.08,7.94,;11.08,6.4,;9.75,5.63,;12.42,5.63,;13.75,6.4,;12.42,4.09,;7.08,2.55,;7.08,1.01,)|
Structure:
Search PDB for entries with ligand similarity: