Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM75342
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM75342
Synonyms:
3-[2-(4-fluorophenyl)-1,2,3,4-tetrazol-5-yl]quinoline | 3-[2-(4-fluorophenyl)-5-tetrazolyl]quinoline | 3-[2-(4-fluorophenyl)tetrazol-5-yl]quinoline | MLS-0067109.0001 | cid_16066565
Type:
Small organic molecule
Emp. Form.:
C16H10FN5
Mol. Mass.:
291.2825
SMILES:
Fc1ccc(cc1)-n1nnc(n1)-c1cnc2ccccc2c1
Structure:
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