Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM75368
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2
IC50
12100±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM75368
Synonyms:
1-(2,3-dihydro-1H-inden-5-yl)-3-(4-sulfamoylphenyl)thiourea | 1-indan-5-yl-3-(4-sulfamoylphenyl)thiourea | MLS-0435634.0001 | cid_970693
Type:
Small organic molecule
Emp. Form.:
C16H17N3O2S2
Mol. Mass.:
347.455
SMILES:
NS(=O)(=O)c1ccc(NC(=S)Nc2ccc3CCCc3c2)cc1
Structure:
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