Reaction Details Report a problem with these data
Target
Oxytocin receptor
Ligand
BDBM75550
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high throughput dose response assay for agonists of the Oxytocin Receptor (OXTR)
EC50
>29905±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay for agonists of the Oxytocin Receptor (OXTR) PubChem Bioassay (2010)[AID] 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Homo sapiens (Human)
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM75550
Synonyms:
MLS001079319 | N-[2-(2-furanyl)-2-(1-piperidinyl)ethyl]-4-[(4-methylphenyl)sulfamoyl]benzamide | N-[2-(2-furyl)-2-piperidino-ethyl]-4-(p-tolylsulfamoyl)benzamide | N-[2-(furan-2-yl)-2-piperidin-1-yl-ethyl]-4-[(4-methylphenyl)sulfamoyl]benzamide | N-[2-(furan-2-yl)-2-piperidin-1-ylethyl]-4-[(4-methylphenyl)sulfamoyl]benzamide | SMR000709510 | cid_24979260
Type:
Small organic molecule
Emp. Form.:
C25H29N3O4S
Mol. Mass.:
467.58
SMILES:
Cc1ccc(NS(=O)(=O)c2ccc(cc2)C(=O)NCC(N2CCCCC2)c2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: