Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM75591
Substrate
n/a
Meas. Tech.
Late-stage fluorescence dose-response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Synthesized compounds
EC50
>50000±n/a nM
Citation
 PubChem, PC Late-stage fluorescence dose-response cell-based assay to identify agonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Synthesized compounds PubChem Bioassay (2010)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM75591
Synonyms:
6-methyl-3-[3-(6-methyl-2-nitro-pyridin-3-yl)oxypropoxy]-2-nitro-pyridine | 6-methyl-3-[3-(6-methyl-2-nitropyridin-3-yl)oxypropoxy]-2-nitropyridine | 6-methyl-3-[3-[(6-methyl-2-nitro-3-pyridinyl)oxy]propoxy]-2-nitropyridine | 6-methyl-3-[3-[(6-methyl-2-nitro-3-pyridyl)oxy]propoxy]-2-nitro-pyridine | CYM5932 | SR-02000000293 | SR-02000000293-1 | cid_7567697
Type:
Small organic molecule
Emp. Form.:
C15H16N4O6
Mol. Mass.:
348.3107
SMILES:
Cc1ccc(OCCCOc2ccc(C)nc2[N+]([O-])=O)c(n1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: