Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM75546
Substrate
n/a
Meas. Tech.
Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based cell-based high throughput dose response assay to identify agonists of the vasopressin 1 receptor (V1R)
EC50
15075±n/a nM
Citation
 PubChem, PC Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based cell-based high throughput dose response assay to identify agonists of the vasopressin 1 receptor (V1R) PubChem Bioassay (2010)[AID] 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM75546
Synonyms:
1-(5-bromo-2-thiophenyl)-2-[2-imino-3-(phenylmethyl)-1-benzimidazolyl]ethanone;hydrobromide | 2-(3-benzyl-2-imino-benzimidazol-1-yl)-1-(5-bromo-2-thienyl)ethanone;hydrobromide | 2-(3-benzyl-2-iminobenzimidazol-1-yl)-1-(5-bromothiophen-2-yl)ethanone;hydrobromide | 2-[2-azanylidene-3-(phenylmethyl)benzimidazol-1-yl]-1-(5-bromanylthiophen-2-yl)ethanone;hydrobromide | MLS000711141 | SMR000280908 | cid_2858900
Type:
Small organic molecule
Emp. Form.:
C20H16BrN3OS
Mol. Mass.:
426.33
SMILES:
Brc1ccc(s1)C(=O)Cn1c2ccccc2n(Cc2ccccc2)c1=N
Structure:
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