Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM75713
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high throughput dose response screening assay for agonists of the vasopressin 1 receptor (V1R)
EC50
18605±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response screening assay for agonists of the vasopressin 1 receptor (V1R) PubChem Bioassay (2010)[AID] 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM75713
Synonyms:
(2E)-7-(diethylamino)-2-(isonicotinoylhydrazono)-2H-chromene-3-carboxamide | MLS000720220 | N-[[3-aminocarbonyl-7-(diethylamino)chromen-2-ylidene]amino]pyridine-4-carboxamide | N-[[3-carbamoyl-7-(diethylamino)-1-benzopyran-2-ylidene]amino]-4-pyridinecarboxamide | N-[[3-carbamoyl-7-(diethylamino)chromen-2-ylidene]amino]isonicotinamide | N-[[3-carbamoyl-7-(diethylamino)chromen-2-ylidene]amino]pyridine-4-carboxamide | SMR000304749 | cid_4646908
Type:
Small organic molecule
Emp. Form.:
C20H21N5O3
Mol. Mass.:
379.4124
SMILES:
CCN(CC)c1ccc2cc(C(N)=O)c(=NNC(=O)c3ccncc3)oc2c1
Structure:
Search PDB for entries with ligand similarity: