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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM75873
Substrate
n/a
Meas. Tech.
Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)
IC50
2900±n/a nM
Citation
 PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM75873
Synonyms:
5-chloranyl-4-(3,4-dimethoxyphenoxy)-2-(4-methylphenyl)pyridazin-3-one | 5-chloro-4-(3,4-dimethoxyphenoxy)-2-(4-methylphenyl)-3-pyridazinone | 5-chloro-4-(3,4-dimethoxyphenoxy)-2-(4-methylphenyl)pyridazin-3-one | 5-chloro-4-(3,4-dimethoxyphenoxy)-2-(p-tolyl)pyridazin-3-one | SR-02000000338 | SR-02000000338-1 | cid_45382327
Type:
Small organic molecule
Emp. Form.:
C19H17ClN2O4
Mol. Mass.:
372.802
SMILES:
COc1ccc(Oc2c(Cl)cnn(-c3ccc(C)cc3)c2=O)cc1OC
Structure:
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