Reaction Details Report a problem with these data
Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM39727
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists
IC50
4745±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM39727
Synonyms:
2-(2-naphthalenyloxy)-N-[2-[[2-(2-naphthalenyloxy)-1-oxoethyl]amino]ethyl]acetamide | 2-(2-naphthoxy)-N-[2-[[2-(2-naphthoxy)acetyl]amino]ethyl]acetamide | 2-naphthalen-2-yloxy-N-[2-(2-naphthalen-2-yloxyethanoylamino)ethyl]ethanamide | 2-naphthalen-2-yloxy-N-[2-[(2-naphthalen-2-yloxyacetyl)amino]ethyl]acetamide | MLS000534009 | N,N'-1,2-ethanediylbis[2-(2-naphthyloxy)acetamide] | SMR000141445 | cid_1787421
Type:
Small organic molecule
Emp. Form.:
C26H24N2O4
Mol. Mass.:
428.4798
SMILES:
O=C(COc1ccc2ccccc2c1)NCCNC(=O)COc1ccc2ccccc2c1
Structure:
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