Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM76068
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM76068
Synonyms:
7-methyl-2-phenyl-4-(p-tolyl)pyrazolo[3,4-d]pyridazine | 7-methyl-4-(4-methylphenyl)-2-phenyl-pyrazolo[3,4-d]pyridazine | 7-methyl-4-(4-methylphenyl)-2-phenylpyrazolo[3,4-d]pyridazine | MLS-0437172.0001 | cid_45917985
Type:
Small organic molecule
Emp. Form.:
C19H16N4
Mol. Mass.:
300.3571
SMILES:
Cc1ccc(cc1)-c1nnc(C)c2nn(cc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: