Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM71590
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay - Set 3
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM71590
Synonyms:
4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(4-methoxyphenyl)methyl-propan-2-yl-amino]ethyl]benzamide | 4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(4-methoxyphenyl)methyl-propan-2-ylamino]ethyl]benzamide | 4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[isopropyl(p-anisyl)amino]ethyl]benzamide | KSC-11-41-1 | KUC104171N | cid_44620896
Type:
Small organic molecule
Emp. Form.:
C29H37N3O4S
Mol. Mass.:
523.687
SMILES:
CCc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)NCCN(Cc1ccc(OC)cc1)C(C)C
Structure:
Search PDB for entries with ligand similarity: