Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM32101
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase
IC50
>100000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase PubChem Bioassay (2010)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM32101
Synonyms:
4-ethoxy-N-[2-keto-7-(1H-1,2,4-triazol-5-ylthio)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxidanylidene-7-(1H-1,2,4-triazol-5-ylsulfanyl)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxo-7-(1H-1,2,4-triazol-5-ylsulfanyl)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxo-7-(1H-1,2,4-triazol-5-ylthio)-1,3-benzoxathiol-5-yl]benzenesulfonamide | 4-ethoxy-N-[2-oxo-7-(4H-1,2,4-triazol-3-ylthio)-1,3-benzoxathiol-5-yl]benzenesulfonamide | MLS000043619 | SMR000020635 | cid_3244674
Type:
Small organic molecule
Emp. Form.:
C17H14N4O5S3
Mol. Mass.:
450.512
SMILES:
CCOc1ccc(cc1)S(=O)(=O)Nc1cc(Sc2nnc[nH]2)c2oc(=O)sc2c1
Structure:
Search PDB for entries with ligand similarity: