Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM76205
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase
IC50
6940±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Placental Alkaline Phosphatase PubChem Bioassay (2010)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM76205
Synonyms:
4-Fluoro-N-[4-hydroxy-3-(1H-[1,2,4]triazol-3-ylsulfanyl)-phenyl]-2-methyl-benzenesulfonamide | 4-fluoranyl-2-methyl-N-[4-oxidanyl-3-(1H-1,2,4-triazol-5-ylsulfanyl)phenyl]benzenesulfonamide | 4-fluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)phenyl]-2-methylbenzenesulfonamide | 4-fluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)phenyl]-2-methyl-benzenesulfonamide | 4-fluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)phenyl]-2-methylbenzenesulfonamide | MLS001217329 | SMR000612865 | cid_1094879
Type:
Small organic molecule
Emp. Form.:
C15H13FN4O3S2
Mol. Mass.:
380.417
SMILES:
Cc1cc(F)ccc1S(=O)(=O)Nc1ccc(O)c(Sc2nnc[nH]2)c1
Structure:
Search PDB for entries with ligand similarity: