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Target
Sentrin-specific protease 8
Ligand
BDBM53450
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
3720±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM53450
Synonyms:
4-(4-bromophenyl)-2-(m-toluoylamino)-3-thenoic acid | 4-(4-bromophenyl)-2-[(3-methylbenzoyl)amino]-3-thiophenecarboxylic acid | 4-(4-bromophenyl)-2-[(3-methylbenzoyl)amino]thiophene-3-carboxylic acid | 4-(4-bromophenyl)-2-[(3-methylphenyl)carbonylamino]thiophene-3-carboxylic acid | 4-(4-bromophenyl)-2-[[(3-methylphenyl)-oxomethyl]amino]-3-thiophenecarboxylic acid | MLS001180414 | O-acyl oxime isatin derivative, 36 | SMR000476038 | cid_1806168
Type:
Small organic molecule
Emp. Form.:
C19H14BrNO3S
Mol. Mass.:
416.288
SMILES:
Cc1cccc(c1)C(=O)Nc1scc(c1C(O)=O)-c1ccc(Br)cc1
Structure:
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