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Target
Sentrin-specific protease 6
Ligand
BDBM43662
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay
IC50
57200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 6
Synonyms:
KIAA0797 | SENP6 | SENP6_HUMAN | SSP1 | SUMO-1-specific protease | SUSP1 | Sentrin-specific protease 6 (SENP6)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
126147.68
Organism:
Homo sapiens (Human)
Description:
Q9GZR1
Residue:
1112
Sequence:
MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQEDQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD
  
Inhibitor
Name:
BDBM43662
Synonyms:
3-phenyl-7-propan-2-yloxy-1-benzopyran-4-one | 3-phenyl-7-propan-2-yloxy-chromen-4-one | 3-phenyl-7-propan-2-yloxychromen-4-one | 7-isopropoxy-3-phenyl-chromone | IPRIFLAVONE | MLS000069470 | SMR000059060 | cid_3747
Type:
Small organic molecule
Emp. Form.:
C18H16O3
Mol. Mass.:
280.3178
SMILES:
CC(C)Oc1ccc2c(c1)occ(-c1ccccc1)c2=O
Structure:
Search PDB for entries with ligand similarity: