Reaction Details Report a problem with these data
Target
Caspase-7
Ligand
BDBM65559
Substrate
n/a
Meas. Tech.
Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7
EC50
>85301±n/a nM
Citation
 PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay (2010)[AID] 
Target
Name:
Caspase-7
Synonyms:
Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase
Type:
Enzyme
Mol. Mass.:
34273.91
Organism:
Homo sapiens (Human)
Description:
P55210
Residue:
303
Sequence:
MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
  
Inhibitor
Name:
BDBM65559
Synonyms:
2-(5-bromo-2-furyl)-4-oxo-4H-chromen-3-yl acetate | MLS001163647 | SMR000498637 | [2-(5-bromanylfuran-2-yl)-4-oxidanylidene-chromen-3-yl] ethanoate | [2-(5-bromofuran-2-yl)-4-oxochromen-3-yl] acetate | acetic acid [2-(5-bromo-2-furanyl)-4-oxo-1-benzopyran-3-yl] ester | acetic acid [2-(5-bromo-2-furyl)-4-keto-chromen-3-yl] ester | cid_1696227
Type:
Small organic molecule
Emp. Form.:
C15H9BrO5
Mol. Mass.:
349.133
SMILES:
CC(=O)Oc1c(oc2ccccc2c1=O)-c1ccc(Br)o1
Structure:
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