Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM77550
Substrate
n/a
Meas. Tech.
Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD
IC50
>39537±n/a nM
Citation
 PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2010)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM77550
Synonyms:
(2E)-1-ethyl-6-methyl-2-[(1-prop-2-enyl-2-quinolin-1-iumyl)methylidene]quinoline;bromide | (2E)-1-ethyl-6-methyl-2-[(1-prop-2-enylquinolin-1-ium-2-yl)methylidene]quinoline;bromide | (2E)-2-[(1-allylquinolin-1-ium-2-yl)methylene]-1-ethyl-6-methyl-quinoline;bromide | 2-[(E)-(1-allylquinolin-2(1H)-ylidene)methyl]-1-ethyl-6-methylquinolinium | MLS000727846 | SMR000306543 | cid_16193032
Type:
Small organic molecule
Emp. Form.:
C25H25N2
Mol. Mass.:
353.4789
SMILES:
CCN1\C(=C\c2ccc3ccccc3[n+]2CC=C)C=Cc2cc(C)ccc12 |c:20|
Structure:
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