Reaction Details Report a problem with these data
Target
RecBCD enzyme subunit RecD
Ligand
BDBM77607
Substrate
n/a
Meas. Tech.
Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD
IC50
>39523±n/a nM
Citation
 PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay (2010)[AID] 
Target
Name:
RecBCD enzyme subunit RecD
Synonyms:
RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
66906.68
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130723
Residue:
608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
  
Inhibitor
Name:
BDBM77607
Synonyms:
2-(1,3-benzodioxol-5-yl)-N-[(5-nitro-2-furanyl)methylideneamino]acetamide | 2-(1,3-benzodioxol-5-yl)-N-[(5-nitro-2-furyl)methyleneamino]acetamide | 2-(1,3-benzodioxol-5-yl)-N-[(5-nitrofuran-2-yl)methylideneamino]acetamide | 2-(1,3-benzodioxol-5-yl)-N-[(5-nitrofuran-2-yl)methylideneamino]ethanamide | MLS002251060 | SMR001313496 | cid_1285782
Type:
Small organic molecule
Emp. Form.:
C14H11N3O6
Mol. Mass.:
317.2536
SMILES:
[O-][N+](=O)c1ccc(\C=N\NC(=O)Cc2ccc3OCOc3c2)o1
Structure:
Search PDB for entries with ligand similarity: