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Target
Protein-arginine deiminase type-4
Ligand
BDBM77613
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical dose response assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4)
IC50
92000±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical dose response assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) PubChem Bioassay (2010)[AID] 
Target
Name:
Protein-arginine deiminase type-4
Synonyms:
PAD4 | PADI4 | PADI4_HUMAN | PADI5 | PDI5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
74078.90
Organism:
Homo sapiens (Human)
Description:
gi_216548487
Residue:
663
Sequence:
MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP
  
Inhibitor
Name:
BDBM77613
Synonyms:
1-[5-(4-chlorophenyl)sulfanyl-4-nitro-thiophen-2-yl]ethanone | 1-[5-(4-chlorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone | 1-[5-[(4-chlorophenyl)thio]-4-nitro-2-thienyl]ethanone | 1-[5-[(4-chlorophenyl)thio]-4-nitro-2-thiophenyl]ethanone | SR-01000633247-1 | cid_2819991
Type:
Small organic molecule
Emp. Form.:
C12H8ClNO3S2
Mol. Mass.:
313.78
SMILES:
CC(=O)c1cc(c(Sc2ccc(Cl)cc2)s1)[N+]([O-])=O
Structure:
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