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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM39583
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM39583
Synonyms:
MLS000075623 | N-(5-Chloro-2-methoxy-phenyl)-2-[4-(5-methyl-benzotriazol-1-yl)-piperidin-1-yl]-acetamide | N-(5-chloranyl-2-methoxy-phenyl)-2-[4-(5-methylbenzotriazol-1-yl)piperidin-1-yl]ethanamide | N-(5-chloro-2-methoxy-phenyl)-2-[4-(5-methylbenzotriazol-1-yl)piperidino]acetamide | N-(5-chloro-2-methoxyphenyl)-2-[4-(5-methyl-1-benzotriazolyl)-1-piperidinyl]acetamide | N-(5-chloro-2-methoxyphenyl)-2-[4-(5-methylbenzotriazol-1-yl)piperidin-1-yl]acetamide | SMR000006502 | cid_653943
Type:
Small organic molecule
Emp. Form.:
C21H24ClN5O2
Mol. Mass.:
413.901
SMILES:
COc1ccc(Cl)cc1NC(=O)CN1CCC(CC1)n1nnc2cc(C)ccc12
Structure:
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