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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM51875
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM51875
Synonyms:
2-amino-4-[4-(4-carbomethoxybenzyl)oxyphenyl]-6-phenyl-1,4-dihydropyrimidine-5-carboxylic acid ethyl ester | 2-amino-4-[4-[(4-methoxycarbonylphenyl)methoxy]phenyl]-6-phenyl-1,4-dihydropyrimidine-5-carboxylic acid ethyl ester | MLS001061287 | SMR000384995 | cid_4969429 | ethyl 2-amino-4-[4-[(4-methoxycarbonylphenyl)methoxy]phenyl]-6-phenyl-1,4-dihydropyrimidine-5-carboxylate | ethyl 2-azanyl-4-[4-[(4-methoxycarbonylphenyl)methoxy]phenyl]-6-phenyl-1,4-dihydropyrimidine-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C28H27N3O5
Mol. Mass.:
485.5311
SMILES:
CCOC(=O)C1C(N=C(N)N=C1c1ccccc1)c1ccc(OCc2ccc(cc2)C(=O)OC)cc1 |c:10,t:7|
Structure:
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