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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78981
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78981
Synonyms:
MLS001199340 | N-[2-[butyl(ethyl)amino]ethyl]-4-keto-5-methyl-thieno[3,2-c]quinoline-2-carboxamide | N-[2-[butyl(ethyl)amino]ethyl]-5-methyl-4-oxidanylidene-thieno[3,2-c]quinoline-2-carboxamide | N-[2-[butyl(ethyl)amino]ethyl]-5-methyl-4-oxo-2-thieno[3,2-c]quinolinecarboxamide | N-[2-[butyl(ethyl)amino]ethyl]-5-methyl-4-oxothieno[3,2-c]quinoline-2-carboxamide | N-{2-[butyl(ethyl)amino]ethyl}-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]quinoline-2-carboxamide | SMR000560348 | cid_20857484
Type:
Small organic molecule
Emp. Form.:
C21H27N3O2S
Mol. Mass.:
385.523
SMILES:
CCCCN(CC)CCNC(=O)c1cc2c(s1)c1ccccc1n(C)c2=O
Structure:
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