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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM60229
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
7857±312 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM60229
Synonyms:
MLS000568342 | N-[N'-(4-Propoxy-benzoyl)-hydrazinocarbothioyl]-propionamide | N-[[(4-propoxybenzoyl)amino]carbamothioyl]propanamide | N-[[(4-propoxybenzoyl)amino]thiocarbamoyl]propionamide | N-[[(4-propoxyphenyl)carbonylamino]carbamothioyl]propanamide | N-[[[oxo-(4-propoxyphenyl)methyl]hydrazo]-sulfanylidenemethyl]propanamide | SMR000177383 | cid_1728272
Type:
Small organic molecule
Emp. Form.:
C14H19N3O3S
Mol. Mass.:
309.384
SMILES:
CCCOc1ccc(cc1)C(=O)NNC(=S)NC(=O)CC
Structure:
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