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Target
X-box-binding protein 1
Ligand
BDBM61056
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
10000±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM61056
Synonyms:
3-Amino-6-trifluoromethoxy-thieno[2,3-b]quinoline-2-carboxylic acid [4-(pyrrolidine-1-sulfonyl)-phenyl]-amide | 3-amino-N-(4-pyrrolidin-1-ylsulfonylphenyl)-6-(trifluoromethoxy)thieno[2,3-b]quinoline-2-carboxamide | 3-amino-N-(4-pyrrolidinosulfonylphenyl)-6-(trifluoromethoxy)thieno[2,3-b]quinoline-2-carboxamide | 3-amino-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-6-(trifluoromethoxy)-2-thieno[2,3-b]quinolinecarboxamide | 3-azanyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)-6-(trifluoromethyloxy)thieno[2,3-b]quinoline-2-carboxamide | MLS000553472 | SMR000171173 | cid_3231291
Type:
Small organic molecule
Emp. Form.:
C23H19F3N4O4S2
Mol. Mass.:
536.547
SMILES:
Nc1c(sc2nc3ccc(OC(F)(F)F)cc3cc12)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCCC1
Structure:
Search PDB for entries with ligand similarity: