Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM31063
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
1310±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM31063
Synonyms:
2-(methylsulfonyl)-4-phenyl-6-(trifluoromethyl)pyrimidine | 2-mesyl-4-phenyl-6-(trifluoromethyl)pyrimidine | 2-methylsulfonyl-4-phenyl-6-(trifluoromethyl)pyrimidine | MLS000044644 | SMR000022588 | cid_3236803
Type:
Small organic molecule
Emp. Form.:
C12H9F3N2O2S
Mol. Mass.:
302.272
SMILES:
CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccccc1
Structure:
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